The STRESS Factor - Part 2 of 3
The Physiological Impact of Stress in Women
Chronic stress impacts the body in numerous ways, and understanding these effects can help you take control of your health. Let’s delve into some of the key areas affected by stress, with a focus on women's health.
Cortisol and Its Impact on Women's Bodies
Cortisol, often referred to as the "stress hormone," plays a central role in how your body responds to stress. In short bursts, cortisol is beneficial, helping to regulate energy, reduce inflammation, and control blood sugar levels. However, when stress is chronic, elevated cortisol levels can lead to several adverse effects, particularly in women. Understanding these effects can help you take control of your well-being. Let’s explore some key areas impacted by stress, focusing on how it uniquely affects women.
Digestive Health
Stress has a significant impact on your digestive health, largely due to the intricate connection between your brain and gut, known as the gut-brain axis. When you're stressed, your body releases hormones such as cortisol and adrenaline, which can disrupt normal digestive processes. This hormonal shift can lead to symptoms like bloating, gas, constipation, or diarrhoea. Chronic stress exacerbates these issues by disturbing the balance of your gut microbiota, reducing the production of digestive enzymes, and impairing nutrient absorption, which can cause further digestive discomfort.
Moreover, stress can weaken your immune system, increasing inflammation in the digestive tract and potentially aggravating existing conditions like irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD). The redirection of blood flow away from the digestive system during stress also slows down digestion, compounding these problems.
Picture this - when our bodies are under chronic stress we may produce less stomach acid which we need for nutrient absorption along with impaired digestion and elimination (think indigestion, loose or dry stools). We need those nutrients to help make our neurotransmitters like serotonin (our happy hormone), and melatonin (our sleep hormone). Chronic stress can lead to nutrient deficiencies further compounding the impact of stress.
Energy and Blood Sugar Regulation
Cortisol plays a crucial role in regulating your body’s energy by controlling the release of glucose into the bloodstream. In ancient times, this surge of energy was essential for survival, like escaping from a predator. Today, however, the stresses of modern life can put your body in a state of perpetual stress, leading to continuous glucose release. When cortisol levels remain elevated due to chronic stress, it disrupts blood sugar balance, leading to energy crashes, cravings for sugary foods, and an increased risk of developing insulin resistance. This is particularly concerning for women, as it can contribute to conditions like type 2 diabetes.
This cycle can be exacerbated by a diet low in protein, which may result in brain fog, reliance on mid-morning sugar or caffeine hits, and frequent snacking as your glucose levels fluctuate throughout the day. These patterns can also hinder any weight management goals, making it even more challenging to achieve and maintain a healthy lifestyle.
Continuous Glucose Monitor output
An example of what blood glucose levels can look like when under chronic stress. Note from waking, the purple line indicates an elevation in blood glucose in absence of any food intake. This continues until 8pm when the first and only meal of the day was consumed.
Disruption of Sleep Patterns
Sleep is a cornerstone of good health, but stress can severely disrupt it. When stress levels are high, cortisol—often called the stress hormone—can interfere with your sleep-wake cycle, making it difficult to fall asleep or stay asleep. This disruption is especially challenging for women, who may already be dealing with sleep issues due to hormonal changes during peri-menopause or menopause.
When you’re stressed, it’s not just your mood that suffers—your sleep takes a hit too. Elevated cortisol levels can throw off your body’s natural circadian rhythm, leading to disturbances in key sleep stages like REM and deep sleep. This often results in poor sleep quality and shorter sleep duration, leaving you feeling fatigued and more stressed the next day.
Chronic stress or an inconsistent sleep schedule can cause cortisol levels to spike at the wrong times, further exacerbating sleep problems and potentially leading to insomnia. This creates a vicious cycle: poor sleep increases stress, and increased stress worsens sleep. The impact goes beyond just feeling tired—over time, it can contribute to more serious health issues like obesity, type II diabetes, and digestive problems, as it disrupts melatonin production, the hormone responsible for regulating sleep.
For more on how sleep affects your health and how to improve it, check out an earlier blog on sleep HERE.
Hormonal Imbalances
Chronic stress has profound effects on thyroid function, which can ripple through various aspects of your health. When stress hampers thyroid hormone activity, it slows down your metabolism, leading to fatigue, weight gain, and difficulty managing a healthy weight—concerns that many women over 35 are particularly attuned to. The brain, which relies heavily on thyroid hormones, may also suffer, contributing to mood disturbances like depression, anxiety, and that frustrating brain fog or forgetfulness you might experience during particularly stressful periods. Beyond these cognitive effects, stress-induced thyroid dysfunction can compromise your immune system, making you more vulnerable to infections and potentially triggering or exacerbating autoimmune conditions, which are more common in women.
Chronic stress exerts a profound influence on your body’s hormonal balance, particularly affecting the delicate interplay between stress hormones and those related to the reproductive system. Elevated cortisol, a primary stress hormone, can interfere with the production of progesterone and oestrogen, two key hormones that regulate your menstrual cycle and reproductive health. This disruption can lead to irregular periods, with cycles becoming shorter, longer, or even skipped entirely. For women in their 30s and 40s, who may already be experiencing shifts in their hormonal balance, the effects of stress can intensify symptoms of PMS, such as mood swings, bloating, and breast tenderness.
Furthermore, during perimenopause, when hormone levels are naturally fluctuating, chronic stress can exacerbate symptoms like hot flashes, night sweats, and sleep disturbances, making this transitional phase even more challenging. For women trying to conceive, the impact of stress on hormone levels can be particularly concerning, as it may affect ovulation and overall fertility. The disruption caused by elevated cortisol doesn’t just stop at reproductive health—it can also contribute to a decline in libido, further straining intimate relationships.
In the longer term, this hormonal imbalance, driven by stress, may also influence the onset of conditions like polycystic ovary syndrome (PCOS) and endometriosis, both of which are closely tied to reproductive hormone levels. The compounded effects of stress and hormone disruption can create a vicious cycle, where stress exacerbates hormonal imbalances, leading to more stress and further health complications. Managing stress effectively is therefore not just about maintaining mental well-being, but also about safeguarding your hormonal health and overall quality of life.
Cognitive Function and Brain Health
Finally, chronic stress can have a profound impact on your brain health. Elevated cortisol levels have been linked to memory problems, difficulty concentrating, and an increased risk of developing anxiety and depression. Women, who are already at a higher risk for these conditions, may find that stress exacerbates their symptoms, making it harder to manage daily tasks and maintain mental clarity.
Far-reaching impact of stress - Conditions that have been linked to stress and poor health include: Allergies, Asthma, Colitis, Constipation, Depression, Diabetes mellitus, Hay Fever, Heart Attack, High Blood Pressure, Indigestion, Menstrual Difficulties, Migraine, Overactive Thyroid Gland, Peptic Ulcers, Rheumatoid Arthritis, Skin Disorders and more.
Conclusion & Teaser for Next Post
The far-reaching effects of stress on women’s health are profound, influencing everything from your digestive system to your sleep quality and hormone levels. In this post, we’ve uncovered how chronic stress disrupts your body’s balance, potentially leading to digestive issues, energy imbalances, sleep disturbances, and hormonal fluctuations.
In the final part of this series, I’ll focus on natural approaches to managing stress. We’ll explore practical strategies such as the benefits of exercise, the importance of quality sleep, and additional techniques to help you reduce stress and enhance your overall well-being. Your path to stress relief is just around the corner.
References and Sources
Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015 Apr-Jun;28(2):203-209.
Kalmbach, D.A., Anderson, J.R. and Drake, C.L., 2018. The impact of stress on sleep: pathogenic sleep reactivity as a vulnerability to insomnia and circadian disorders. Journal of sleep research, 27(6), p.e12710.
Leigh SJ, Uhlig F, Wilmes L, Sanchez-Diaz P, Gheorghe CE, Goodson MS, Kelley-Loughnane N, Hyland NP, Cryan JF, Clarke G. The impact of acute and chronic stress on gastrointestinal physiology and function: a microbiota-gut-brain axis perspective. J Physiol. 2023 Oct;601(20):4491-4538.
Valsamakis, G., Chrousos, G. and Mastorakos, G., 2019. Stress, female reproduction and pregnancy. Psychoneuroendocrinology, 100, pp.48-57.
Wong H, Singh J, Go RM, Ahluwalia N, Guerrero-Go MA. The Effects of Mental Stress on Non-insulin-dependent Diabetes: Determining the Relationship Between Catecholamine and Adrenergic Signals from Stress, Anxiety, and Depression on the Physiological Changes in the Pancreatic Hormone Secretion. Cureus. 2019 Aug 24;11(8):
Yaribeygi H, Panahi Y, Sahraei H, Johnston TP, Sahebkar A. The impact of stress on body function: A review. EXCLI J. 2017 Jul 21;16:1057-1072
